Fertility and pregnancy in rheumatoid arthritis and systemic lupus erythematosus

Table 3 Relative risk for adverse pregnancy outcomes in RA and SLE

	RA*	SLE
Hypertension/preelampsia	Possibly	20 %
Preterm delivery including PPROM	Odds ratio 1.5 compared to controls	40 %
C-section rate	Increased	Increased
SGA	Yes	Yes
Fetal/neonatal death	No	17 %
Anti-Ro/SSA, Anti-La/ SSB positive patients
Neonatal lupus	14–20 %	14–20 %
CCHB	2 %, recurrence rate 17 %	2 %, recurrence rate 17 %

*RA patients are less commonly positive for anti-Ro/SS-A and anti-La/SS-B antibodies than are patients with SLE, but when antibody-positive these patients are subject to the same risk for neonatal lupus in their offspring

ISSN: 2054-7099