From: Incidence, diagnosis and management of tubal and nontubal ectopic pregnancies: a review
Absolute Contraindications | Relative Contraindications |
---|---|
Clinical instability or significant pain suggestive of ruptured EP | Presence of fetal cardiac activity |
Heterotopic pregnancy with viable and desired IUP | β-hCG level over 5000 mIU/mL |
Liver function tests more than 2 times the upper limit of normal | An ectopic mass size greater than 4 cm in largest dimension |
White blood cell count of <1500/uL | Patient refusal of blood transfusion |
Platelet count <100,000/uL | Patient inability to follow up |
Creatinine ≥1.5 mg/dL | |
Current breastfeeding | |
Active pulmonary disease | |
Active peptic ulcer disease | |
Moderate to severe anemia | |
Sensitivity to methotrexate |