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Table 3 Studies of PCOS and ovarian cancer risk

From: Polycystic ovary syndrome and risk of endometrial, ovarian, and breast cancer: a systematic review

Author

Year

Study design

Ovarian Cancer Cases (n)

Overall result RR (95% CI)

Harris

2016

Case–control (US)

1513

1.0 (0.60–1.5)

Gottschau

2015

Registry Cohort (Danish)

10

1.8 (0.8–3.2)a

Shen

2015

Registry Cohort (Taiwan)

11

1.0 (0.2–4.6)a

Barryb

2014

Meta-analysis

3363

1.4 (0.9–2.2)a

Bodmer

2011

Case–control (UK)

1611

1.6 (0.7–4.1)a

Brintonc

2010

Cohort (US)

12

1.8 (0.9–3.1)a

Olsen

2008

Case–control (Australia)

1276

1.1 (0.6–2.0)

Schildkraut

1996

Case–control (US)

476

2.4 (1.0–5.9)a

Rossing

1994

Cohort (US)

11

2.4 (0.2–22.5)

  1. a Effect estimate not adjusted for BMI
  2. b This meta-analysis includes the studies by Bodmer, Olsen, and Schildkraut
  3. c In this study, androgen excess or menstrual disorders was evaluated rather than PCOS