Skip to main content

Table 4 Studies of PCOS and breast cancer risk

From: Polycystic ovary syndrome and risk of endometrial, ovarian, and breast cancer: a systematic review

Author

Year

Study design

Breast Cancer Cases (n)

Overall result RR (95% CI)

Gottschau

2015

Registry Cohort (Danish)

59

1.1 (0.8–1.4)a

Shen

2015

Registry Cohort (Taiwan)

44

1.6 (0.9–2.8)a

Barryb

2014

Meta-analysis

3618

1.0 (0.6–1.4)a

Ghasemi

2010

Case–control (Iran)

166

0.7 (0.3–1.5)a

Brintonc

2010

Cohort (US)

89

1.3 (1.1–1.6)a

Terryd

2006

Cohort (US)

2267

0.8 (0.6–1.0)

Wild

2000

Cohort (UK)

49

1.3 (0.6–2.8)

Anderson

1997

Cohort (US)

883

1.2 (0.7–2)

Talamini

1997

Case–control (Italy)

2569

0.9 (0.4–1.8)

Gammon

1991

Case–control (US)

4730

0.47 (0.3–0.9)a

Coulame

1983

Cohort (US)

12

1.5 (0.8–2.6)

  1. a Effect estimate not adjusted for BMI
  2. b This meta-analysis includes the studies by Ghasemi, Anderson, and Talamini
  3. c In this study, androgen excess or menstrual disorders was evaluated rather than PCOS
  4. d In this study, infertility due to ovulatory disorders was evaluated rather than PCOS
  5. e In this study, chronic anovulation syndrome was evaluated rather than PCOS