Ovarian morphology is associated with insulin resistance in women with polycystic ovary syndrome: a cross sectional study

Table 2 Logistic Regression Analysis of Follicle Number and Ovarian Volume as Dichotomous Variables

	Follicle Number ≥12 vs <12	Follicle Number ≥25 vs <25	Ovarian Volume >10 cc vs ≤ 10 cc
	AOR (95%CI)	AOR (95%CI)	AOR (95%CI)
Fasting Insulin >19 μIU/mL	2.2 (0.7–7.0)	0.9 (0.5–1.8)	1.8 (1.0–3.4)
HOMA-IR >4	1.2 (0.4–3.4)	0.8 (0.4–1.6)	1.9 ^a (1.0–3.6)
Fasting Glucose >100 mg/dL	0.9 (0.3–2.9)	0.5 (0.2–1.4)	1.8 (0.8–4.0)
2 h Glucose >140 mg/dL	0.9 (0.3–2.9)	0.4 (0.1–1.0)	1.3 (0.6–2.7)
Waist Circ >89 cm	0.9 (0.4–2.2)	0.7 (0.4–1.3)	1.6 (0.9–2.6)
Free Testosterone >6.8 pg/mL	4.2 (0.5–33.2)	2.2 (1.0–4.9)	1.8 (0.8–4.0)
Total Testosterone >53 ng/dL	0.9 (0.2–3.6)	1.5 (0.6–3.3)	1.1 (0.5–2.6)
Abnormal DHEAS	1.1 (0.4–3.0)	1.0 (0.5–2.1)	0.7 (0.4–1.3)
Acanthosis Nigricans Present	0.7 (0.3–1.5)	1.0 (0.6–1.6)	1.4 (0.9–2.3)

i. The largest available ovarian volume and single ovary follicle number was used
ii. Adjusted OR were controlled for age
iii. DHEAS measurements were performed at multiple laboratory sites, the reference cutoff for each site was used to determine normal/abnormal status
iv. HOMA-IR cutoff chosen to reflect more significant insulin resistance [22]
v. Fasting Insulin cutoff chosen to reflect the reference range of the laboratory used by majority of patients in the study
^a indicates p < 0.05

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