| |
Vaginal n = 227
|
IM n = 182
|
P value
|
|---|
|
Any side effect n (%)
|
76 (33.5%)
|
53 (29%)
|
0.3
|
|
Perineal irritation n (%)
|
7 (3%)
|
3 (1.6%)
|
0.3
|
|
Rectal itching n (%)
|
12 (5%)
|
1 (0.5%)
|
0.006
|
|
Vaginal bleeding n (%)
|
10 (4.4%)
|
4 (2.2%)
|
0.2
|
|
Rectal leak n (%)
|
22 (9.7%)
|
0
|
0.00016
|
|
Vaginal leak n (%)
|
35 (15.4%)
|
2 (1.1%)
|
<0.0001
|
|
Constipation n (%)
|
22 (9.7%)
|
4 (2.2%)
|
0.002
|
|
Discomfort after administration n (%)
|
3 (1.3%)
|
33 (18%)
|
<0.0001
|
|
Abdominal pain n (%)
|
3 (1.3%)
|
1 (0.5%)
|
0.4
|
|
Diarrhea n (%)
|
1 (0.4%)
|
0
|
0.4
|
|
Bloating n (%)
|
1 (0.4%)
|
0
|
0.4
|
|
Hematoma formation n (%)
|
0
|
3 (1.65%)
|
0.05
|
-
aChi-square test was used
