Skip to main content

Table 3 Pre- and post-treatment outcomes stratified by patient aetiology

From: ART implantation failure and miscarriage in patients with elevated intracellular cytokine ratios: response to immune support therapy

  n Control Outcomes (Pre) Intervention Outcomes (Post) Sig (P)
Pregnancies Miscarriages (MR%) Pregnancies Miscarriages (MR%)  
RIF 56 0 0 (NA) 44 16 (36.4) 0.015
RPL 46 148 137 (92.6) 33 13 (39.4) < 0.0001
- RM2 25 55 51 (92.7) 17 6 (35.3) < 0.0001
- RM3+ 19 87 82 (94.3) 15 7 (46.7) < 0.0001
Other 32 32 23 (71.9) 26 15 (57.7) 0.50
Total 134 180 160 (89.0) 103 44 (42.7) < 0.0001
  1. Population outcomes in the study population (n = 134) both before (Control outcomes) and after (intervention outcomes) immunomodulation, stratified by patient aetiology. RIF patients presented with repeated implantation failure (no pregnancy following at least 2 transfers of good quality embryos). RPL are patients with recurrent pregnancy loss, the RM2 and RM3+ subgroups refer to either 2 or ≥ 3 consecutive losses, while the remainder are non-consecutive losses. “Other” refers to secondary infertility patients with features of RIF/RPL, not meeting the strict criteria for either group. Significance calculated using McNemar’s test