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Table 4 Pre- and post-implantation outcomes stratified by treatment modality employed

From: ART implantation failure and miscarriage in patients with elevated intracellular cytokine ratios: response to immune support therapy

 

Control Cycles (Pre)

Intervention Cycles (Post)

OR (95 %CI)

Sig (p)

ETs

Embryos

GSs

IR (%)

ETs

Embryos

GSs

IR (%)

IVF

75

125

25

20.0

55

79

22

27.8

1.54 (0.8–3.0)

0.196

ICSI

48

87

9

10.3

69

80

15

18.8

2.0 (0.8–4.9)

0.127

FET

30

44

1

2.3

67

96

28

29.2

17.7 (2.3–134.9)

0.006

DE

24

39

3

7.7

60

92

41

44.6

9.6 (2.8–33.6)

0.0004

Overall

177

295

38

12.9

251

347

106

30.5

3.0 (2.0–4.5)

0.0001

  1. Implantation rates (IR) in the studied group of 134 patients, before (Pre) and following (Post) immunomodulatory therapy. Significant improvements seen in IR following immunomodulatory therapy in FET and particularly DE cycles. ETs Embryo transfers, GSs Gestational sacs seen, IVF in-vitro fertilisation cycles, ICSI intracytoplasmic sperm injection cycles, FET Frozen embryo transfer cycles, DE Donor egg cycles