Table 1 Clinical characteristics of the patients involved in this study
| Â | Transfusion-dependent patients | Patients undergoing HSCT | p-value | ||
|---|---|---|---|---|---|
Number | 52 | 43 | Â | ||
Age, years (mean ± SD) | 27.31 ± 4.34 | 23.64 ± 6.11 | 0.84 | ||
Tanner Staging n (%) | P1 | 1 (1.9%) | 1 (2.3%) | 0.40 | |
P2 | 8 (15.4%) | 9 (20.9%) | |||
P3 | 18 (34.6%) | 10 (23.3%) | |||
P4 | 20 (38.5%) | 8 (18.6%) | |||
P5 | 5 (9.6%) | 6 (14%) | |||
missing | – | 9 (20.9%) |  | ||
Right testis (mean ± SD) | 11.10 ± 5.24 | 11.84 ± 9.22 | 0.005 | ||
Left testis (mean ± SD) | 11.80 ± 5.77 | 11.06 ± 8.27 | 0.6 | ||
FSH (mean ± SD) | 3.44 ± 2.12 | 8.17 ± 10.41 | 0.003 | ||
LH (mean ± SD) | 4.49 ± 2.76 | 6.33 ± 3.82 | 0.22 | ||
Testosterone (mean ± SD) | 4.61 ± 3.15 | 4.04 ± 2.57 | 0.1 | ||
TSH (mean ± SD) | 3.67 ± 2.38 | 3.64 ± 2.64 | 0.7 | ||
T4 (mean ± SD) | 7.59 ± 1.91 | 16.82 ± 3.67 | 0.003 | ||
Hypogonadism, n (%) | 16 (30.8%) | 15 (36.6%) | 0.35 | ||
| Â | 10 (19.2%) | 6 (14.6%) | 0.38 | ||
Semen | Volume | Normal | 38 | 9 | 0.00 |
Low | 9 | 23 | |||
Dry ejaculate | 5 | 11 | |||
Viscosity | High | 2 | 2 | 0.21 | |
Normal | 44 | 29 | |||
Low | 1 | 1 | |||
Dry ejaculate | 5 | 11 | |||
Agglutination | Few | 1 | 1 | 0.21 | |
Rare | 1 | 1 | |||
None | 45 | 30 | |||
Dry ejaculate | 5 | 11 | |||
Sperm | Concentration | Normal | 31 | 16 | 0.017 |
Oligospermia | 9 | 5 | |||
Azoospermia | 12 | 22 | |||
Total motility | Normal | 31 | 16 | 0.017 | |
< 40% | 9 | 5 | |||
Azoospermia | 12 | 22 | |||
Progressive motility | Normal | 26 | 14 | 0.017 | |
< 32% | 14 | 7 | |||
Azoospermia | 12 | 22 | |||
Shape | Normal | 32 | 19 | 0.005 | |
< 4% | 8 | 1 | |||
Azoospermia | 12 | 22 | |||