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Table 3 Pregnancy Outcome of Patients in Surveillance vs Standard protocols & Change in Hormones vs No Change

From: Measuring serum estradiol and progesterone one day prior to frozen embryo transfer improves live birth rates

 Surveillance protocol (N = 524)Standard protocol (N = 379)aOR (95% CI)p-valuePatients with change in hormones (N = 175)Patients without change in hormones (N = 349)aOR (95% CI)p-value
Positive hCGa366/524 (70%)231/379 (61%)1.6 (1.2, 2.2)0.002115/175 (66%)251/349 (72%)0.8 (0.5, 1.2)0.3
Live birth268 (51%)149 (39%)1.6 (1.2, 2.2)0.00183 (47%)185 (53%)0.8 (0.6, 1.2)0.4
Spontaneous abortion51 (10%)38 (10%)1.0 (0.7, 1.7)0.913 (7%)38 (11%)0.6 (0.3, 1.2)0.2
Therapeutic abortion4 (0.8%)2 (0.5%)1.4 (0.2, 8.1)0.71 (0.6%)3 (0.9%)0.7 (0.1, 7.4)0.8
Stillborn (> 20 weeks)2 (0.4%)2 (0.5%)0.9 (0.1, 6.6)0.91 (0.6%)1 (0.3%)2.0 (0.1, 35.0)0.6
Ectopic Pregnancy1 (0.2%)2 (0.5%)0.5 (0.1, 6.2)0.60 (0%)1 (0.3%)
Biochemical Pregnancy40 (7.6%)38 (10%)0.8 (0.5, 1.3)0.417 (10%)23 (7%)1.7 (0.9, 3.4)0.1
  1. All analyses were performed using logistic regression adjusted for age, BMI, number of embryos transferred and PGT
  2. a = Positive hCG represents summation of all pregnancy outcomes listed below this row