Skip to main content

Table 2 Genotype and allele frequencies of TNF-α 238 and 308 variants in RPL patient and control groups. Statistical significance was defined at the level of 5% (p < 0.05)

From: Association of Tumor Necrosis Factor-α -308G>A, -238G>A and -376G>A polymorphisms with recurrent pregnancy loss risk in the Greek population

 

Total

RPL group

Control group

X2

p-value

(N = 111)

(N = 62)

(N = 49)

TNF-α − 238/308, n (%)

   

3.749

0.694

GG/GG

50 (45.05)

25 (40.32)

25 (51.02)

  

GG/GA

39 (35.14)

24 (38.71)

15 (30.61)

  

GG/AA

12 (10.81)

6 (9.68)

6 (12.24)

  

GA/GG

2 (1.80)

2 (3.23)

0 (0)

  

GA/GA

7 (6.31)

4 (6.45)

3 (6.12)

  

GA/AA

1 (0.90)

1 (1.61)

0 (0)

  

Allele, n (%)

   

0.621

0.431

G

362 (81.53)

199 (80.24)

163 (83.16)

  

A

82 (18.47)

49 (19.76)

33 (16.84)