Articles

Staging of the estrous cycle and induction of estrus in experimental rodents: an update

Determination of the phases of the estrous cycle and induction of estrus (heat) in experimental animals remains useful, especially in reproductive function research.

Authors: Ayodeji Folorunsho Ajayi and Roland Eghoghosoa Akhigbe

Indicators of male fertility potential in adult patients with beta-thalassemia major: a comparative study between patients undergone allogeneic stem cell transplantation and transfusion-dependent patients

Allogeneic hematopoietic stem cell transplantation (HSCT) remains the only potentially curative treatment for thalassemia major (TM). Infertility and its indicators have been assessed in transfusion dependent ...

Authors: Tahereh Rostami, Mohammad Amir Mohammadifard, Shahla Ansari, Azadeh Kiumarsi, Nasrollah Maleki, Amir Kasaeian, Fatemeh Aghamahdi, Soroush Rad and Ardeshir Ghavamzadeh

Risk factors of tubal infertility in a tertiary hospital in a low-resource setting: a case-control study

Infertility is the inability to sustain a pregnancy in a woman with regular (2–3 times per week) unprotected sexual intercourse for a period of 1 year. This is a major public health problem that remains under-...

Authors: Thomas Obinchemti Egbe, Theophile Nana-Njamen, Felix Elong, Robert Tchounzou, Andre Gaetan Simo, Gaelle Padjip Nzeuga, Cedric Njamen Nana, Emmanuella Manka’a, Charlotte Tchente Nguefack and Gregory Edie Halle-Ekane

Should we transfer poor quality embryos?

To evaluate if it is safe and effective to transfer poor quality embryos.

Authors: Anastasia Kirillova, Sergey Lysenkov, Maria Farmakovskaya, Yulia Kiseleva, Bella Martazanova, Nona Mishieva, Aydar Abubakirov and Gennady Sukhikh

Public reporting of IVF outcomes influences medical decision-making and physician training

Since 1992 ART clinics have been required to report outcome data. Our objective was to assess practitioners’ opinions of the impact of public reporting of assisted reproductive technology (ART) outcomes on tre...

Authors: Stephanie Gunderson, Emily S. Jungheim, Caleb B. Kallen and Kenan Omurtag

Bayesian smoothed small-areas analysis of urban inequalities in fertility across 1999–2013

Since the 2008 economic crisis in Spain, overall fertility has continued to decrease, while urban inequalities have increased. There is a general lack of studies of fertility patterns in small-areas of Spanish...

Authors: Brenda Biaani León-Gómez, Mercè Gotsens, Marc Marí-Dell’Olmo, Ma. Felicitas Domínguez-Berjón, Miguel Ángel Luque-Fernandez, Unai Martin, Maica Rodríguez-Sanz and Gloria Pérez

Impact of genital Chlamydia trachomatis infection on reproductive outcomes among infertile women undergoing tubal flushing: a retrospective cohort at a fertility centre in Uganda

The impact of current C. trachomatis on clinical pregnancy and live birth rates among women undergoing tubal flushing is largely unknown. This study aimed to investigate whether current female genital C. trachoma...

Authors: Anthony Kayiira, Daniel Zaake, Michael Webba Lwetabe and Peter Sekweyama

IVF outcomes after hysteroscopic metroplasty in patients with T- shaped uterus

T- shaped uterus may be associated with infertility and adverse pregnancy outcomes. Hysteroscopic metroplasty may improve the reproductivity for these cases. To our knowledge, there is no data in literature ab...

Authors: Esra Uyar, Deniz Usal, Belgin Selam, Mehmet Cincik and Tayfun Bagis

Use and pattern of previous care received by infertile Nigerian women

Prevalence of infertility in sub-Saharan Africa is high yet fertility care, its development and access is limited in resource-poor countries like Nigeria so infertile women resort to different forms of treatme...

Authors: Amina Mohammed-Durosinlorun, Joel Adze, Stephen Bature, Amina Abubakar, Caleb Mohammed, Matthew Taingson and Lydia Airede

Data mining polycystic ovary morphology in electronic medical record ultrasound reports

Polycystic ovary syndrome (PCOS) is characterized by hyperandrogenemia, oligo-anovulation, and numerous ovarian cysts. Hospital electronic medical records provide an avenue for investigating polycystic ovary m...

Authors: Jay Jojo Cheng and Shruthi Mahalingaiah

Association of Female Sexual Dysfunction and Fertility: a cross sectional study

Sexual function plays an essential role in the bio-psychosocial wellbeing and quality of life of women and disturbances in sexual functioning often result in significant distress. Female sexual dysfunction (FS...

Authors: Felix Mwembi Oindi, Alfred Murage, Valentino Manase Lema and Abraham Mwaniki Mukaindo

Vaginal cuff dehiscence following controlled ovarian stimulation recognized during egg retrieval

Vaginal cuff dehiscence is a rare complication of hysterectomy. Those who choose to undergo controlled ovarian stimulation (COS) and oocyte cryopreservation following hysterectomy must be aware that elevated a...

Authors: Alexandra Peyser, Avner Hershlag, Antoinette Sakaris and Tomer Singer

Number of motile spermatozoa inseminated and pregnancy outcomes in intrauterine insemination

To determine whether age modifies the effect of the number of motile spermatozoa inseminated (NMSI) as a predictor of success in Intrauterine Insemination (IUI).

Authors: Palma G. Gubert, Jessica Pudwell, Dean Van Vugt, Robert L. Reid and Maria P. Velez

15 years of transcriptomic analysis on endometrial receptivity: what have we learnt?

Authors: Soumaya Messaoudi, Imane EL Kasmi, Amelie Bourdiec, Kimberley Crespo, Laurence Bissonnette, Cecile Le Saint, François Bissonnette and Isaac-Jacques Kadoch

Case report of pelvic tuberculosis resulting in Asherman’s syndrome and infertility

Approximately one-third of the world’s population is infected with Mycobacterium tuberculosis, and it is a leading cause of infertility in endemic countries. The global incidence of tuberculosis (TB) is growing a...

Authors: Mary Louise Fowler and Shruthi Mahalingaiah

Epidemiology of infertility and characteristics of infertile couples requesting assisted reproduction in a low-resource setting in Africa, Sudan

Infertility is a big health problem worldwide. Few data exist on infertility in Sudan.

Authors: Osama G. Elhussein, Mohamed A. Ahmed, Suliman O. Suliman, leena I. Yahya and Ishag Adam

Perceptions, expectations and challenges among men during in vitro fertilization treatment in a low resource setting: a qualitative study

Partner support is very important in alleviating the burden of infertility related stress and although understudied, partner coping patterns also play a key role in the other partner’s ability to cope with the...

Authors: Daniel Zaake, Anthony Kayiira and Imelda Namagembe

Knowledge and attitudes regarding elective oocyte cryopreservation in undergraduate and medical students

To assess knowledge and attitudes regarding elective oocyte cryopreservation among female undergraduate students (UG) and medical students (MS) in Eastern Virginia.

Authors: Arnold M. Mahesan, Seifeldin Sadek, Hadi Ramadan, Silvina Bocca, Anthea B. M. Paul and Laurel Stadtmauer

Case report: interventional radiology’s potential role for in vitro fertilization post ovarian transposition and pelvic radiation

Ovarian transposition is a procedure that can help preserve fertility for female patients requiring radiation in the abdominopelvic region. However, the displacement of ovaries from its original anatomic locat...

Authors: Benjamin Jang, Aaron Rohr, Paras P. Vakharia, Zachary Collins, Courtney Marsh, Isabella Herrera and Thomas Fahrbach

Ethnic disparities in fertility and its determinants in Nigeria

High fertility rate has been consistently reported in Nigeria. The three major ethnic groups in Nigeria, Hausa/Fulani, Igbo, and Yoruba have different socio-cultural identities particularly those that relate t...

Authors: Ayo Stephen Adebowale

Antimullerian hormone is a predictor of live birth in patients with recurrent pregnancy loss

Ovarian reserve testing is not routinely performed in the evaluation of recurrent pregnancy loss (RPL). The objective of this study was to determine if AMH levels are predictive of live birth rate in RPL patie...

Authors: Gayathree Murugappan, Lora Shahine and Ruth B. Lathi

Congenital Zika syndrome arising from sexual transmission of Zika virus, a case report

Sexual transmission of Zika virus is well documented and pregnant women are advised to abstain or use barrier protection if a sexual partner has risk for Zika infection. However, to date there has not been a d...

Authors: Christina D. Yarrington, Davidson H. Hamer, Wendy Kuohung and Aviva Lee-Parritz

ART implantation failure and miscarriage in patients with elevated intracellular cytokine ratios: response to immune support therapy

The origins of adverse reproductive outcome can be multifactorial, but the contribution of the maternal immune system is considered debatable. Elevated intracellular cytokine ratios have been proposed, althoug...

Authors: Conor Harrity, Lyuda Shkrobot, David Walsh and Kevin Marron

Diagnosis and management of a heterotopic pregnancy and ruptured rudimentary uterine horn

Heterotopic pregnancies implanted in a rudimentary uterine horn account for 1 in 2–3 million gestations, and confer significant risk of morbidity due to uterine rupture and hemorrhage.

Authors: Paula C. Brady, Rose L. Molina, Michael G. Muto, Brenna Stapp and Serene S. Srouji

The impact of endometrial thickness (EMT) on the day of human chorionic gonadotropin (hCG) administration on pregnancy outcomes: a 5-year retrospective cohort analysis in Malaysia

Chances of pregnancy in relation to endometrial thickness (EMT) remain elusive albeit some literatures suggest poorer pregnancy outcomes below the threshold of 6-7 mm, notwithstanding others perceive detriment...

Authors: Joe Mee Chan, Alvin Isaac Sukumar, Magendra Ramalingam, Surinder Singh Ranbir Singh and Mohamad Farouk Abdullah

Determinants of change in fertility pattern among women in Uganda during the period 2006–2011

Studies on fertility in Uganda have attributed fertility reduction to a shift in the overall characteristics of women of reproductive age. It is not clear whether the reduction in fertility is due to changing ...

Authors: Paulino Ariho, Allen Kabagenyi and Abel Nzabona

Responses to fertility treatment among patients with cancer: a retrospective cohort study

Cancer treatments have significant negative impacts on female fertility, but the impact of cancer itself on fertility remains to be clarified. While some studies have shown that compared with healthy women, th...

Authors: A. V. Dolinko, L. V. Farland, S. A. Missmer, S. S. Srouji, C. Racowsky and E. S. Ginsburg

Pyosalpinges after hysterosalpingography in a patient with lower genital tract infection and managed by laparoscopic surgery in a resource low tertiary hospital case report and literature review

Pyosalpinges (a complication of pelvic inflammatory disease) is infection of the fallopian tubes and the morbidity associated with it has major health implications. We are reporting a case of pyosalpinges diag...

Authors: Thomas Obinchemti Egbe, Fidelia Mbi Kobenge, Metogo Mbengono Junette Arlette and Eugene Belley-Priso

Anti-oxidant mediated normalisation of raised intracellular cytokines in patients with reproductive failure

Raised intracellular cytokine ratios (CKR) are proposed as a significant risk factor for adverse reproductive outcome. An elevated cytokine ratio, such as between TNFa and/or IFNg to IL-10 is associated with r...

Authors: Kevin Marron, John F. Kennedy and Conor Harrity

Characterization of reproductive endocrinology and infertility (REI) fellowship applicants: guiding our mentees toward success

Advanced subspecialty training in reproductive endocrinology and infertility (REI) entails a competitive application process with many data points considered. It is not known what components weigh more heavily...

Authors: Jason Franasiak, Daniel Kaser, Linnea Goodman, George Patounakis, Caroline Juneau, Scott Morin, Shelby Neal, William Schlaff and Richard Scott

Intramuscular progesterone (Gestone) versus vaginal progesterone suppository (Cyclogest) for luteal phase support in cycles of in vitro fertilization–embryo transfer: patient preference and drug efficacy

The requirement for luteal phase support (LPS) in stimulated IVF cycles is well established, however drug choice, and route of administration and duration of use are not. This report evaluates patients’ prefer...

Authors: Amal Yaseen Zaman, Serdar Coskun, Ahmed Abdullah Alsanie and Khalid Arab Awartani

Fertility differential of women in Bangladesh demographic and health survey 2014

The aim of this study was to examine the fertility differential of women age 15 to 49 using data from Bangladesh Demographic and Health Survey 2014- a survey of women who were born from 1963 to 1999.

Authors: Shongkour Roy and Sharif Mohammed Ismail Hossain

Fertility with early reduction of ovarian reserve: the last straw that breaks the Camel’s back

Diminished fertility and poor ovarian response pose a conundrum to the experts in the field of reproductive medicine. There is limited knowledge about the risk factors of diminished ovarian reserve other than ...

Authors: Sabahat Rasool and Duru Shah

Vitamin D binding protein is lower in infertile patients compared to fertile controls: a case control study

The importance of vitamin D in general health as well as in human reproductive success has been an area of focus. A better understanding of vitamin D metabolism, particularly vitamin D binding protein, is impo...

Authors: Jason Franasiak, Sue Shapses, Wei Sun, Richard Scott and Xiangbing Wang

Magnetic resonance imaging performance for diagnosis of ovarian torsion in pregnant women with stimulated ovaries

To determine if asymmetric ovarian edema on non-contrast MRI can be used to distinguish torsed from non-torsed stimulated ovaries in pregnant women.

Authors: Elizabeth Asch, Jesse Wei, Koenraad J. Mortele, Kathryn Humm, Kim Thornton and Deborah Levine

Contraception and fertility transition in AMHARA National Regional State of ETHIOPIA: an application of BONGAARTS’ model

The overall decline of fertility in Amhara National Regional State between 2000 and 2011 was the highest in Ethiopia. The aim of the present study was to determine the most significant proximate determinant of...

Authors: Nega Mihret Alazbih, Getachew Nibret Tewabe and Tariku Dejene Demissie

Perceptıon scale of barrıers to contraceptıve use: a methodologıcal study

The objective of this study was to design and develop the Perception Scale of Barriers to Contraceptive Use (PSBCU) as a measurement tool for the qualitative assessment of the barriers and obstacles women perc...

Authors: Selma Sen, Aynur Cetinkaya and Aysel Cavuslar

Alcohol and fertility: how much is too much?

Alcohol use is prevalent in the United States. Given that a substantial portion of the drinking population is of reproductive age, it is not uncommon for couples who are attempting conception, or for women who...

Authors: Kristin Van Heertum and Brooke Rossi

Fertility preservation training for obstetrics and gynecology fellows: a highly desired but non-standardized experience

Despite a large body of data suggesting that delivery of fertility care to cancer patients is inconsistent and frequently insufficient, there is a paucity of literature examining training in fertility preserva...

Authors: Elizabeth J. N. Miller, Lisa M. Cookingham, Teresa K. Woodruff, Ginny L. Ryan, Karen M. Summers, Laxmi A. Kondapalli and Divya K. Shah

Ovarian morphology is associated with insulin resistance in women with polycystic ovary syndrome: a cross sectional study

Polycystic ovary syndrome (PCOS) is a very common disorder well known to be associated with insulin resistance and metabolic disease. Insulin resistance is likely involved in the promotion of the PCOS reproduc...

Authors: Sara Pittenger Reid, Chia-Ning Kao, Lauri Pasch, Kanade Shinkai, Marcelle I. Cedars and Heather G. Huddleston

Cardiovascular risk factors among women with self-reported infertility

Amongst women with certain types of ovulatory disorder infertility, the studies are conflicting whether there is an increased risk of long-term cardiovascular disease risk. This paper evaluates the association...

Authors: Shruthi Mahalingaiah, Fangui Sun, J. Jojo Cheng, Erika T. Chow, Kathryn L. Lunetta and Joanne M. Murabito

“I am anxious and desperate”: psychological experiences of women with infertility in The Greater Accra Region, Ghana

Research has shown that infertility affects millions of couples worldwide. Infertility is considered one of the most difficult life experiences and can result in psychological consequences for couples, especia...

Authors: Ernestina S. Donkor, Florence Naab and Deborah Y. Kussiwaah

Discrete survival model analysis of a couple’s smoking pattern and outcomes of assisted reproduction

Cigarette smoking has been associated with worse infertility treatment outcomes, yet some studies have found null or inconsistent results.

Authors: Jose C. Vanegas, Jorge E. Chavarro, Paige L. Williams, Jennifer B. Ford, Thomas L. Toth, Russ Hauser and Audrey J. Gaskins

Tablet terminals: a useful tool to explain in vitro fertilization treatment

Explanations that involve medical care treatment take time. This also applies to explanations of in vitro fertilization (IVF) in the field of infertility treatment. This is because the cause of infertility dif...

Authors: Atsushi Yanaihara, Shirei Ohgi, Kenichirou Motomura and Takumi Yanaihara

Preconception consultations with Maternal Fetal Medicine for obese women: a retrospective chart review

Obesity is associated with impaired fertility and pregnancy complications, and preconception weight loss may improve some of these outcomes. The purpose of this study was to evaluate the quality and effectiven...

Authors: Charlotte M. Page, Elizabeth S. Ginsburg, Randi H. Goldman and Chloe A. Zera

Polycystic ovary syndrome and risk of endometrial, ovarian, and breast cancer: a systematic review

Polycystic ovary syndrome (PCOS) is a complex endocrine disorder with an estimated prevalence of 4–21% in reproductive aged women. The altered metabolic and hormonal environment among women with PCOS may incre...

Authors: Holly R. Harris and Kathryn L. Terry

A simple, less invasive stripper micropipetter-based technique for day 3 embryo biopsy

Preimplantation genetic screening (PGS) is an important procedure for in vitro fertilization (IVF). A key step of PGS, blastomere removal, is abundant with many technical issues. The aim of this study was to c...

Authors: Luciano Cedillo, Azucena Ocampo-Bárcenas, Israel Maldonado, Francisco J. Valdez-Morales, Felipe Camargo and Esther López-Bayghen

Successful pregnancy with donor eggs in-vitro fertilization after premature ovarian insufficiency in a tertiary hospital in a low-income setting: a case report

Premature Ovarian Insufficiency (POI) is classically defined as 4–6 months of cessation of menses (amenorrhea) in women under 40, associated with menopausal level of serum gonadotropins FSH > 40 IU/L and hypo-...

Authors: Thomas Obinchemti Egbe, Carine Youta Wafo, Berthe Bebey Bollo, Christian Pany, Monique Jong Onomo and Guy Sandjon

Lifestyle and in vitro fertilization: what do patients believe?

Patients have many beliefs regarding lifestyle factors and IVF outcomes.

Authors: Brooke V. Rossi, Leah Hawkins Bressler, Katharine F. Correia, Shane Lipskind, Mark D. Hornstein and Stacey A. Missmer

Efficiency of metaphase II oocytes following minimal/mild ovarian stimulation in vitro fertilization

An inverse relationship between oocyte efficiency and ovarian response was reported in conventional IVF. The purpose of this study was to report metaphase II (MII) oocyte efficiency according to oocyte yield i...

Authors: John J. Zhang, Mingxue Yang and Zaher Merhi